This is actually fanart for a show of which I have seen all of one episode so far.
These two are Madoka (pink) and Homura (purple) from Puella Magi Madoka Magica, it's a new magical girl show, and I'm afraid I got on the bandwagon for it almost immediately.
I just can't help it: I don't care for moe styled shows, but Madoka actually has an unusually cool 'look' to it, moe character designs nonwithstanding. Madoka and her family live in a city that looks pretty much like it was designed from the ground up by Norman Foster, it's so ultramodern, and the magical girl attacks look like some sort of reality-melting acid trip.
And on top of that, Madoka already has a mysterious rival and/or stalker magical girl named Homura, who likes to corner her and say portentous things about doom (I think she means well) and that looks like it may be headed in a Nanoha-ish direction. Also, the cat/rabbit mascot may or may not be EVIL.